Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
toxicity to reproduction
Remarks:
other: read across
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
Anonymous
Year:
2010
Bibliographic source:
OECD Toolbox v2.0, November 2010

Materials and methods

Test guideline
Guideline:
other: read across
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzene-1,2,4,5-tetracarboxylic acid, compound with 4,5-dihydro-2-phenyl-1H-imidazole (1:2)
EC Number:
259-226-5
EC Name:
Benzene-1,2,4,5-tetracarboxylic acid, compound with 4,5-dihydro-2-phenyl-1H-imidazole (1:2)
Cas Number:
54553-91-2
Molecular formula:
C10H6O8.2C9H10N2
IUPAC Name:
benzene-1,2,4,5-tetracarboxylic acid, compound with 4,5-dihydro-2-phenyl-1H-imidazole (1:2)

Test animals

Species:
rat
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Duration of treatment / exposure:
45d

Results and discussion

Results: P0 (first parental generation)

Effect levels (P0)

Dose descriptor:
LOEL
Effect level:
65.4 mg/kg bw/day (nominal)
Based on:
test mat.
Sex:
not specified

Overall reproductive toxicity

Reproductive effects observed:
not specified

Applicant's summary and conclusion