Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Dermal absorption

Currently viewing:

Administrative data

Endpoint:
dermal absorption
Type of information:
other: read-across from (Q)SAR from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
other: QSAR database
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Guideline:
other: REACH guidance on QSARs R.6, May/July 2008
Principles of method if other than guideline:
Danish (Q)SAR database report

Test material

Constituent 1
Chemical structure
Reference substance name:
2-ethylhexyl laurate
EC Number:
243-697-9
EC Name:
2-ethylhexyl laurate
Cas Number:
20292-08-4
Molecular formula:
C20H40O2
IUPAC Name:
2-ethylhexyl laurate

Results and discussion

Absorption in different matrices:
Dermal absorption of 2-ethylhexyl laurate was predicted to be 0.00010 mg/cm2/event (very low).

Applicant's summary and conclusion