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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

72 -h-ErC50 = nominal 150 mg/L (95% confidence limits: 130 -176 mg/L)
72 -h-NOECr = nominal 10 mg/L.

Key value for chemical safety assessment

EC50 for freshwater algae:
150 mg/L
EC10 or NOEC for freshwater algae:
10 mg/L

Additional information

In a test according to OECD Guideline 201, the toxicity against algae was tested with "Phosphoric acid, C9-11-branched and linear alkyl esters, potassium salts and Phosphoric acid, C13-15-branched and linear alkyl esters, potassium salts; 50/50" . The 72 -h-ErC50 was determined to be nominal 150 mg/L (95% confidence limits: 130 -176 mg/L) and the 72 -h-NOECr to be 10 mg/L.

Rationale for Read-across

The key study on acute toxicity to algae was made with the read-across source substance: Phosphoric acid, C9-11-branched and linear alkyl esters, potassium and Phosphoric acid, C13-15-branched and linear alkyl esters,

potassium salts; 50/50.

The test substance has a sufficient simmilar chemical structure compared to the registration substance:

  • comparable C-chain length distribution
  • comparable ratio of mono/di/tri-alkyl ester
  • comparable identiy and amount of by-products

Differences between test and registration substance:

  • the source substance is the potassium salt of the registration substance. It contains potassium cations and the corresponding base of the phosphoric acid ester.
  • The registration substance has 2 protons that, in aqueous solution, will easily protonate water molecules, resulting in the same corresponding base of the phosphoric acid ester and H3O+. aqueous solution of the test substance has a neutral to slightly basic pH (see description of fish test) whereas the the aqueous solution of the registration substance has low pH

The algae test medium contains both, a sodium carbonate buffer and potassium phosphate buffer. Due to this buffer capacity, protones of the registration substance in testing solution are substituted with sodium and potassium cations.


No different test results are expected from the source substance test compared to the registration substance test as a consequence of the identity of relevant chemical species in the test preparation.