Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 932-020-9 | CAS number: 246538-71-6
Endpoint summary
Administrative data
Description of key information
Not irritating to skin.
Not irritating to eyes.
Key value for chemical safety assessment
Additional information
No data were available on skin irritation induced by Hydrocarbons, C8 -C9, isoalkanes. Therefore, the skin irritation potential was estimated from read-acros from studies on the related substance Hydrocarbons, C7 -C9, n-alkanes, isoalkanes, cyclics. One skin irritation potential study of the test substance was performed according to OECD 404 (Shell, 1987). The other one was conducted according to Draize, 1959 (Shell, 1977). Under the test conditions, the test substance was not irritating to the skin.
The eye irritation potential of the hydrocarbons, C7-C9, isoalkanes, belonging to the same category as C8 -C9, isoalkanes, was determined by instillation of 0.1 mL of the test material into the conjunctival sac of 3 rabbits (ExxonMobil, 2004). Ocular reactions were examined and scored 1, 24, 48, 72 hours after application. At the 1 hour evaluation, conjunctival redness (grade 2) was observed in all animals. Conjunctival redness (grade 0-1) was also noted in all animals at the 72 hour evaluation. All redness was reversible within 7 days. No corneal opacity, iritis or conjunctival chemosis was noted in any of the 3 rabbits. Two further studies, performed according to OECD 404) showed that no ocular irritation in any animal at any time point could be observed for the compounds ISOPAR E and ISOPAR C (both studies from ExxonMobil, 1997). In another study of ExxonMobil (1977) conducted similar to OECD 405, at 1 hour after administration, 4 of 6 animals showed slight erythema which completely subsided by the 4 hour observation. The remaining 2 animals showed slight or moderate erythema, slight edema, and slight discharge. These irritating effects were fully reversible within 72 hours after administration.Under the test conditions, the test substance was not irritating to the eyes.
Justification for classification or non-classification
Based on the available data, hydrocarbons, C8-C9, isoalkanes were considered as not being skin irritant.
The available data on the eye irritating potential of hydrocarbons, C8-C9, isoalkanes, are conclusive but not sufficient for classification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
