Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 939-331-9 | CAS number: 1394155-71-5
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
72h EC50 (Desmodesmus subspicatus; growth rate) = 34 mg/L (nominal concentration, EU Method C.3)
72h EC10 (Desmodesmus subspicatus; biomass) = 19 mg/L (nominal concentration, EU Method C.3)
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 34 mg/L
- EC10 or NOEC for freshwater algae:
- 19 mg/L
Additional information
Since no reliable toxicity tests with algae are available for C16-18 and C18 unsatd. AS Na (CAS 1394155-71-5), in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read-across to another structurally related category member was conducted. Read-across data from C16-18AS Na (CAS 68955-20-4) were used, since toxicity of alkyl sulfates is dependent in the carbon chain length.
Three reliable studies investigating toxic effects of C16-18AS Na (CAS 68955-20-4) to freshwater algae are available. The key non-GLP study was performed with Desmodesmus subspicatus according to EU Method C.3 (Richterich 2001). Growth inhibition caused by the test substance was determined after 24, 48 and 72 hours of exposure to eleven test concentrations up to 3000 mg/L substance of 55.5% purity (equal to 1650 mg a.i./L). No analytical monitoring is available. The results show that the 72-hour EC50 value for growth rate was 34 mg a.i./L and for biomass 30 mg a.i./L (nominal concentrations). The EC10 for biomass was 19 mg a.i./L (nominal concentrations).
Moreover, the non-GLP study by Steber (1988) with Chlorella vulgaris performed according to Algal Assay Procedure Bottle Test, National Research Program, US EPA (1971) is available. Algae were exposed to the test substance for 14 days. The reported EC50 value for growth rate is 14.4 mg a.i./L and the EC10 value for growth rate is 28.6 mg/L (nominal concentrations, no analytical monitoring available). Another non-GLP test reported by Steber (1988) was done with Desmodesmus subspicatus according to the procedure for growth inhibition toxicity testing by UBA Berlin, 1984. Algae were exposed to the test substance for 96 hours. The EC50 value for growth rate was 57.6 mg a.i./L (nominal concentration, no analytical monitoring available). The EC10 value for growth rate was 25.5 mg a.i./L (nominal concentration).
Due to structure and property similarities with the tested category member it can be concluded that the above results apply also to C16-18 and C18 unsatd.AS Na (CAS 1394155-71-5). The 72-hour EC50 for algae growth rate is 34 mg/L and the EC10 value is 19 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
