Registration Dossier
Registration Dossier
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EC number: 215-293-2 | CAS number: 1319-77-3
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
As cresol isomers are neither expected to persist in sediment nor to accumulate in sediment-dwelling organisms any toxic effect can be excluded.
Key value for chemical safety assessment
Additional information
No data on toxicity to sediment organisms are available. In accordance with section 1 of REACH Annex XI, the study does not need to be conducted as the trigger values for sediment assessment are not exceeded. According to chapter R.7b of the RIP guidance documents (ECHA, 2008) trigger values for sediment assessment are a log Kow or log Koc of ≥ 3, taking into account the adsorption behaviour to sediment and the bioaccumulation potential of the test substance. o-Cresol, m-cresol, and p-cresol have low log Koc values ranging between 1.34 and 1.75, which suggest a low potential of these isomers to adsorb to soil and sediment. Log Kow values of 1.94 to 1.96 also suggest a low bioaccumulation potential, which is supported by bioaccumulation factors of 10.7 to 20. As cresol isomers are neither expected to persist in sediment nor to accumulate in sediment-dwelling organisms any toxic effect can be excluded and studies on toxicity to sediment organisms are scientifically unjustified.
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