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EC number: 225-306-3 | CAS number: 4767-03-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
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- Additional toxicological data

Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Remarks:
- Danish (Q)SAR Database
- Justification for type of information:
- 1. SOFTWARE: Danish (Q)SAR Database
2. MODEL: EPI MPBPWIN v1.43
3. SMILES OR OTHER IDENTIFIERS USED AS INPUT FOR THE MODEL: C(=O)(O)C(C)(CO)CO - Qualifier:
- no guideline followed
- Specific details on test material used for the study:
- SMILES (used for QSAR prediction): C(=O)(O)C(C)(CO)CO
- Test no.:
- #1
- Temp.:
- ca. 25 °C
- Vapour pressure:
- ca. 0 mm Hg
- Remarks on result:
- other: QSAR prediced (EPI MPBPVP v.1.43) model
- Conclusions:
- Within the Danish (Q)SAR Database report for the test item, an vapour pressure of 0.00000124 mm Hg (0.00016 Pa) is reported, using the EPI MPBPVP model.
- Executive summary:
Within the Danish (Q)SAR Database report for the test item, an vapour pressure of 0.00000124 mm Hg (0.00016 Pa) is reported, using the EPI MPBPVP model.
- Endpoint:
- vapour pressure
- Type of information:
- (Q)SAR
- Remarks:
- estimated by calculation
- Adequacy of study:
- key study
- Study period:
- 2009-12-01
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Remarks:
- The vapour pressure has been calculated with two different calculation programs. According to “Endpoint specific guidance R.7.1.5.3” SPARC and MPBPWIN are recommended as calculation programs for vapour pressure.
- Justification for type of information:
- Vapour pressure was predicted to be below 1.0 Pa and is therefore experimentally very difficult to perform. Therefore, two different programs were used to estimate the vapour pressure by calculation. The highest value is reported.
- Principles of method if other than guideline:
- The vapour pressure has been calculated with two different calculation programs.
According to “Endpoint specific guidance R.7.1.5.3” SPARC and MPBPWIN are recommended as calculation programs for vapour pressure. - GLP compliance:
- no
- Type of method:
- other: calculation
- Specific details on test material used for the study:
- Calculation method, hence no physical Bis-MPA was used
- Key result
- Test no.:
- #1
- Temp.:
- 25 °C
- Vapour pressure:
- 0.001 Pa
- Remarks on result:
- other: Calculation method SPARC
- Test no.:
- #2
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: Calculation method MPBPWIN (v1.43) Modified Grain method
- Conclusions:
- The vapour pressure of Bis-MPA is estimated to be 0.00058 Pa at 25 °C using SPARC calculation method.
- Executive summary:
Using two different calculation programs according to "Endpoint specific guidance R.7.1.5.3" and reporting the higher value, the vapour pressure of Bis-MPA was estimated to be 0.00058 Pa at 25 °C.
Referenceopen allclose all
Description of key information
The vapor pressure of Bis-MPA was calculated to be 0.00058 Pa at 25 °C using the SPARC method (Backmann, 2010).
As supportive infomation, the vapour pressure of the Danish (Q)SAR Database was calculated. The test item has a predicted vapour pressure of 0.00000124 mm Hg (0.00016 Pa), using the EPI MPBPVP model.
Key value for chemical safety assessment
- Vapour pressure:
- 0.001 Pa
- at the temperature of:
- 25 °C
Additional information
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