Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information


Currently viewing:

Administrative data

Description of key information

Two carcinogenicity studies have been performed with DMH with both the rat and mouse. The substance is not considered to be oncogenic neither in rat nor in mice. NOAEL > 1000 mg/kg bw/day.

Key value for chemical safety assessment

Carcinogenicity: via oral route

Endpoint conclusion
Dose descriptor:
1 000 mg/kg bw/day

Justification for classification or non-classification

Additional information

The estimation of No Observed Effect Level of DMH greater than 1000 mg/kg bw/day was based upon the observation of no-effect in the neoplastic histopathological data of the high dose group. The absence of effect was due to non-statistically significant observations in the test.