Registration Dossier
Registration Dossier
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EC number: 212-751-3 | CAS number: 866-81-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The calculated EC50(48h) for the effects of Tricobalt dicitrate to Daphnia magna is 1.16 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1.16 mg/L
Additional information
Data on acute single-species toxicity tests resulting in high quality L(E)C50 values for freshwater invertebrates (n=11) are summarised in Table 2 of the WHO CICAD document, 2006 (see attached document).
Acute data for Daphnia magna were extracted and used in the effects assessment. The LC50(48h) values ranged from 1.1 mg cobalt chloride hexahydrate/L (Biesinger & Christensen, 1972) to 6 mg cobalt sulfate/L, resulting in recalculated values from 0.9 to 3,9 mg Tricobalt dicitrate/L. The key study (Khangarot and Ray, 1989) showed an acute toxicity resulting in an EC50(48h) of 1.49 mg cobalt chloride hexahydrate/L (equivalent to 1.16 mg Tricobalt dicitrate/L).
Studies on other invertebrate species such as rotifers, different copepod species and crayfish showed a range of EC50 values from 3.4 to 27.8 mg cobalt chloride hexahydrate/L (equivalent to 2.7 to 21.7 mg Tricobalt dicitrate/L).
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