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Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
3.7 mg/L

Additional information

A study was conducted to evaluate the acute toxicity of the test substance, C8-18 and C18-unsatd. MIPA, to Daphnia magna under static conditions according to OECD Guideline 202, in compliance with GLP. The substance was not completely soluble in test medium at the concentrations tested and hence the preparation included a 2 d magnetic stirring period followed by overnight settlement and subsequent collection of the Water Soluble Fraction (WSF). Twenty daphnia per test group (4 vessels, 5 Daphnia/vessel) were exposed at concentrations of 4.6, 10, 22, 46 and 100% of the WSF prepared at a loading rate of 100 mg/L. The total test period was 48 h. Samples for measurement of Total Organic Carbon (TOC) in solution were taken at the start and the end of the test period. The average exposure concentrations were calculated to correspond to 2.0, 4.8, 10 and 21 mg/L for the test groups containing 10, 22, 46 and 100% WSF, respectively. Under the study conditions, the 48 h EC50 was determined to be 3.7 mg/L (95% CI: 3.3-4.4 mg/L). The 48 h NOEC was 2.0 mg/L (Migchielsen, 2010).