Exo-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl methacrylate

Adsorption / desorption

Administrative data

Endpoint:

adsorption / desorption: screening

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-05-23

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2007

Report date:

2017

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

HPLC estimation method

Test material

Test material information

Constituent 1

Reference substance name:

Exo-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl methacrylate

EC Number:

231-403-1

EC Name:

Exo-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl methacrylate

Cas Number:

7534-94-3

Molecular formula:

C14H22O2

IUPAC Name:

1,7,7-trimethylbicyclo[2.2.1]hept-2-yl methacrylate

Test material form:

liquid

Specific details on test material used for the study:

- Name of test material (as cited in study report): IBOMA Isobornyl methacrylate
- Physical state: Clear colourless liquid
- Storage conditions: Ambient temperature (10 °C to 30°C), protected from light
- Expiry date: November 04, 2017

Radiolabelling:

no

Study design

HPLC method

Details on study design: HPLC method:

HPLC equipment: HPLC System Agilent 1100 series: H PLC pump G 1311 A, autosampler
G1313A, column oven G1316A, degasser G1322A, variable wavelength detector C,1314A

Column: Stationary phase: Zorbax Eclipse XDB-CN, Agilent Particle size: 5 μm, pore size: 80 A, Material: stainless steel, dimensions: 150 mm x 4.6 mm, Serial No.: USBJ002539, Column temperature: 25 °C

Mobile phase (eluent): Methanol/ demineralized water 55:45 % (v/v), pH = 5.8, isocratic elution
Flow rate: 1 ml/min
lnjection volume: 10 μI
Detection: 210 nm (dead time marker), 210 nm (calibration substances), 208 nm (test item)

lnjection amounts:
Dead time marker: 4.62 μg
Calibration substances:0. 73 - 1.16 μg
Testitem: 0.38 μg

The test item was dissolved in methanol and diluted from 0.1 ml to 1 ml with eluent. The dead time marker and the calibration substances were dissolved in methanol and diluted from 0.1 ml to 1.0 ml with eluent.

Batch equilibrium or other method

Analytical monitoring:

yes

Results and discussion

Adsorption coefficient

Key result

Type:

log Koc

Value:

3.71 dimensionless

Temp.:

25 °C

Remarks on result:

other: HPLC-Merthod

Any other information on results incl. tables

Determination of the dead timet0

Dead time marker	tR/min 1 st Measurement	tR/ min 2 nd Measurement	tR/min Mean
Formamide	1.708	1.708	1.708

 

Dead time to = 1.71

Calibration data-1stmeasurement

Calibration substance	1st lnj. tR/min	k	log	logKoca
Acetanilide	2.168	0.27	-0.57	1.25
Atrazin	2.603	0.52	-0.28	1.81
Triadimenol	3.568	1.09	0.04	2.40
Linuron	4.115	1.41	0.15	2.59
Pyrazophos	7.325	3.29	0.52	3.65
Diclofop-methyl	10.279	5.02	0.70	4.20
4,4' DDT	34.548	19.23	1.28	5.63

Regression:1ogK0c=a+b·logk

Parameters:

a 2.444

b = 2.408

r2= 0.9919

logK0c ofthe test item-1stmeasurement

Testltem	1st lnj. tR/min	k	log	logKoca
Isobornyl methacylate	7.567	3.43	0.54	3.73

 

Calibration data-2 ndmeasurement

Calibration substance	1st lnj. tR/min	k	log	logKoca
Acetanilide	2.174	0.27	-0.56	1.25
Atrazin	2.609	0.53	-0.28	1.81
Triadimenol	3.566	1.09	0.04	2.40
Linuron	4.135	1.42	0.15	2.59
Pyrazophos	7.338	3.30	0.52	3.65
Diclofop-methyl	10.427	5.10	0.71	4.20
4,4' DDT	35.638	19.87	1.30	5.63

Regression:1ogK0c=a+b·log k

Parameters:

a =2.435

b = 2.397

r2= 0.9926

logK0c ofthe test item-2 ndmeasurement

Testltem	1st lnj. tR/min	k	log	logKoca
Isobornyl methacylate	7.510	3.40	0.53	3.71

 

Result: mean adsorption coefficient logKoc of 3.7.

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

Log Koc of Isobornyl methacrylate was measuerd in OECD 121 Guideline , HPLC Method. Result. Log Koc=3.71

Executive summary:

Log Koc of Isobornyl methacrylate was measured in OECD 121 Guideline test, HPLC Method. Result. Log Koc=3.71

NOTE: Any of data in this dataset are disseminated by the European Union on a right-to-know basis and this is not a publication in the same sense as a book or an article in a journal. The right of ownership in any part of this information is reserved by the data owner(s). The use of this information for any other, e.g. commercial purpose is strictly reserved to the data owners and those persons or legal entities having paid the respective access fee for the intended purpose.