Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 268-103-5 | CAS number: 68002-88-0 This substance is identified by SDA Substance Name: C16-C22 alkyl carboxylic acid and SDA Reporting Number: 21-005-00.
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A PNEC is not derived since no adverse effects were observed in long-term tests in the range of the water solubility of the test substances.
Key value for chemical safety assessment
Additional information
For the members of the fatty acid category four chronic tests are available conducted with pure homologues of different chain lengths. The tested homologues were: decanoic acid (C10 - CAS 334-48-5), lauric acid (C12 - CAS 143-07-7), myristic acid (C14 - CAS 544-63-5) and palmitic acid (C16 - CAS 57-10-3).
As for the fatty acid, C16 -22 mixture (CAS 68002 -88 -0), no study is available, a read-across is performed to palmitic acid (C16).
For the evaluation of chronic effects of palmitic acid (C16: CAS 57 -11 -4) on aquatic invertebrates, daphnids were tested in a limit-test over a period of 21 days (NITE, 2008). The semi-static experiment was conducted according to OECD 211 in compliance with GLP-requirements. The used test concentration of 0.51 mg/L (nominal) corresponding to a mean measured value (time weighted mean) of 0.22 mg/L was above the reported water solubility limit. No effects were observed on daphnids at this test concentration and thus the NOEC is reported to be 0.22 mg/L.
Concluding from the results reported for palmitic acid C16 no chronic risk is expected for the considered fatty acid (CAS 68002 -88 -0).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
