Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original reference not translated, only short abstract available

Data source

Reference
Title:
No information
Author:
Kosachevskaya PI (1967) Hygienische Bestimmung der maximal zugelassenen Konzentrationen von o-, m- und p-Nitrotoluol in Wasserreservoiren. Gig Toksikol Pestits Klin Otravlenii 5: 92-99; zitiert in Chem Abstr 73: 91015e (1970)

Materials and methods

GLP compliance:
no
Remarks:
GLP was not mandatory at the time of the study

Test material

Constituent 1
Chemical structure
Reference substance name:
4-nitrotoluene
EC Number:
202-808-0
EC Name:
4-nitrotoluene
Cas Number:
99-99-0
Molecular formula:
C7H7NO2
IUPAC Name:
1-methyl-4-nitrobenzene

Test animals

Species:
mouse

Administration / exposure

Route of administration:
other: no data

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
6 800 mg/kg bw

Applicant's summary and conclusion