Registration Dossier
Registration Dossier
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EC number: 210-817-6 | CAS number: 623-84-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
A 72-hr Acute Toxicity Test with Pseudokirchneriella subcapitata was conducted with DOWANOL PGDA. The test conduct followed OECD Guideline
201 and met GLP requirements. The 72-hr EC50 for growth rate was determined to be 273 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 273 mg/L
- EC10 or NOEC for freshwater algae:
- 118 mg/L
Additional information
A short-term aquatic toxicity test was conducted with the freshwater green algae, Pseudokirchneriella subcapitata for 72 -hrs exposed to propane-1,2 -diyl diacetate (DOWANOL PGDA) with growth rate inhibition as the endpoint. The test followed OECD 201, met GLP requirements and therefore was consider the key study with a Klimisch score of 1. Test concentrations were set at 3.2, 10, 32, 100, 320, 1000 mg/L with a laboratory water control. The 72 -hr EC50 value was 273 mg/L (C.I. 264 - 285 mg/L). The No Observed Effect Concnetration (NOEC) was calcuated to be 34.9 and the EC10 was 118.4 mg/L.
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