Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 231-102-5 | CAS number: 7439-93-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity test in algae with lithium is not
available. Consequently, read-across was applied using study results
obtained from lithium hydroxide monohydrate. Lithium hydroxide
monohydrate was tested for toxicity to algae in an 72 h static test
according to EU Guideline C.3 and OECD Guideline 201. The results showed
an EC50 value of 153.44 mg/L based on growth rate. Based on a
read-across approach an EC50 (growth rate) value of 25.6 mg/L and a NOEC
value of 1.65 mg/L were calculated for lithium metal.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 25.6 mg/L
- EC10 or NOEC for freshwater algae:
- 1.65 mg/L
Additional information
The influence of the test item lithium hydroxide monohydrate on the growth of Pseudokirchneriella subcapitata was investigated in a 72 h static test according to EU method C.3 and OECD Guideline No. 201 in 2010.
The test item had a statistically significant inhibitory effect on the growth based on the average specific growth rate, yield and areas under the curves of Pseudokirchneriella subcapitata after the exposure period of 72 hours in the concentration range of 20 - 160 mg/L test item/L (Bonferroni t-Test, alpha=0.05). The test concentration of 20 mg/L was determined as the 72-hour LOEC. The results showed an EC50 value of 41.62 mg/L based on biomass and 153.44 mg/L based on growth rate. The NOEC based on growth rate for lithium hydroxide monohydrate was 10 mg/L.
Based on a read-across approach an EC50 (growth rate) value of 25.6 mg/L and a NOEC value of 1.65 mg/L were calculated for lithium metal.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
