Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-605-4 | CAS number: 85-43-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Algal growth inhibition: ErC50= 65.3 mg/L; EyC50 = 61.4 mg/L; NOEC = 25 mg/L
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 65.3 mg/L
- EC10 or NOEC for freshwater algae:
- 25 mg/L
Additional information
Algal growth inhibition to the unicellular freshwater green algaPseudokirchneriella subcapitatahas been investigated according to OECD/EU test methods. THPA was found to inhibit the growth after 72 hours exposure, EC50 values for inhibition of specific growth rate (ErC50) and yield (EyC50) being 65.3 mg/L and 61.4 mg/L, respectively. The potential for recovery from the observed effects was established.
In accordance with ECHA guidance oninformation requirements and chemical safety assessment, Chapter R.7b: Endpoint specific guidance, theErC50 endpoint is used in DNEL derivation. This is because use of values based on biomass cannot be applied to an analysis of results from a system in exponential growth without logarithmic transformation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
