Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
eye irritation
Remarks:
no data
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: There are some studies available on isomers of the registration substance. The forecast uncertainty of read across makes it difficult to classify only based on this data.

Data source

Reference
Reference Type:
publication
Title:
2,4-Dichloranilin, 2,5-Dichloranilin, 3,4-Dichloranilin, BUA Stofbericht 140
Year:
1993
Bibliographic source:
S. Hirzel Verlagsgesellschaft 1994, Beratergremium für umweltrelevante Altstoffe (BUA)

Materials and methods

Principles of method if other than guideline:
No details on methods available
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2,4-dichloroaniline
EC Number:
209-057-8
EC Name:
2,4-dichloroaniline
Cas Number:
554-00-7
Molecular formula:
C6H5Cl2N
IUPAC Name:
2,4-dichloroaniline
Constituent 2
Chemical structure
Reference substance name:
2,5-dichloroaniline
EC Number:
202-455-2
EC Name:
2,5-dichloroaniline
Cas Number:
95-82-9
Molecular formula:
C6H5Cl2N
IUPAC Name:
2,5-dichloroaniline
Constituent 3
Chemical structure
Reference substance name:
3,4-dichloroaniline
EC Number:
202-448-4
EC Name:
3,4-dichloroaniline
Cas Number:
95-76-1
Molecular formula:
C6H5Cl2N
IUPAC Name:
3,4-dichloroaniline

Results and discussion

Any other information on results incl. tables

The isomers 2,4 -, 2,5 - and 3,4 -dichloroaniline show weak to moderate eye-irritating properties. Based on this datas a classification as skin irritating is suitable.

Applicant's summary and conclusion

Interpretation of results:
irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU