Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-808-3 | CAS number: 110-85-0
Endpoint summary
Administrative data
Description of key information
Additional information
Acute toxicity studies are available for fish daphnia and algae. For fish the 96h LC50 is >100 mg/L. For daphnia the 48h LC50 for piperazine is observed to be 105.4 mg/L (95% CI: 86.6 - 127.2 mg/L). For Algae 72h ErC50 and ErC10 for piperazine is observed to be 153.1 and 109.3 mg/L respectively.
From the available data Daphnia appear to be the most sensitive aquatic species. The value for long-term toxicity to Daphnia which resulted in a NOEC of 12.5 mg/L is used for calculation of PNEC.
The long-term toxicity to fish is derived using the Acute-to-Chronic (ACR) approach. Based on the available 96-h LC50 > 100 mg/L (NITE, 2003) a NOEC for the long-term toxicity to fish of > 1 mg/L was derived.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
