Registration Dossier
Registration Dossier
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EC number: 604-314-4 | CAS number: 142844-00-6
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Description of key information
No effects were seen in an OECD 421 (see section 7.8.1.1 )screening study. No further studies are planned.There are no reports of any reproductive toxic effect from mineral fibres, exposure is via inhalation and effects seen are in the lung, clearance of fibres is via the gut and the faeces, so exposure of the reproductive organs is extremely unlikely.
Additional information
No effects were seen in an OECD 421 (see section 7.8.1.1) screening study
Toxicity to reproduction: other studies
Additional information
Based on the toxicokinetic assessment the substance is of low toxicological activity and there is no evidence of systemic absorption occurring via relevant routes of exposure
Justification for classification or non-classification
No effects have been seen and toxicokinetic considerations make any effect unlikely therefore there is no reason to classify for reproductive effects
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
