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Ecotoxicological information

Endpoint summary

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Description of key information

As the test substance does not solve in water, the mechanism of partitioning from the water phase and thus uptake by diffusion from the water phase does not take place. Thus exposure of terrestrial organisms to the test substance may occur only by oral intake of solid particles of the test substance. An effect in the organism would then be caused by internal partitioning of test substance (as modelled by equilibrium partitioning and for highly lipophilic substance with an additional factor of 10, see Guidance Document on Information Requirements and Chemical Safety Assessment R.10 and R.16). However, for activated carbon no absorption is expected (see toxicokinetic assessment). The absence of effects from oral intake of activated carbon is supported by the results of an acute toxicity study with rats where no adverse effects were observed after oral exposure to 2000 mg/kg (C80453). To demonstrate the absence of effects in terrestrial organisms, a reproduction toxicity test with earthworms (OECD 222) was performed with Activated Carbon - High Density Skeleton. This study was read across to Activated Caron- Low Density Skeleton in this dossier. The NOEC in this study was observed to be 1000 mg/kg soil. Therefore further testing with terrestrial organisms is waived.

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