Registration Dossier
Registration Dossier
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EC number: 205-500-4 | CAS number: 141-78-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
S. subspicatus (mg/l): NOEC (72hr): >100, EC10 (48hr) 2300, EC50 (48hr) 5600
S capricornutum (mg/l): NOEC (96hr) 2000
S pannonicus (mg/l): NOEC (48hr) 1000
C. pyrenoidosa (mg/l): NOEC (48hr) >1000
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 5 600 mg/L
- EC10 or NOEC for freshwater algae:
- 1 000 mg/L
Additional information
A 72-hour GLP limit test study conducted according to OECD TG 201 using Scenedesmus subspicatus reported a NOEC in excess of 100 mg/l. A 48-hour study using Scenedesmus subspicatus reported an EC50value of 5600 mg/l and a NOEC of 2300mg/l. Studies which could not be rated for reliability due to a lack of information also reported consistent NOEC values of 1000mg/l or above in other algal species. Overall, the toxicity of ethyl acetate to algae appears to be very low. The key study is only a limit study. Only one study reports an EC50 and this is used for this key parameter. The EC10 is derived from the lowest reported actual value (which is greater than the value from the reliable limit test.) There is no reliable data for marine algae
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