Registration Dossier
Registration Dossier
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EC number: 431-850-4 | CAS number: 7456-68-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: 92/69/EWG, B.1; OECD 401
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
Test animals
- Species:
- other: rat, Fischer 344
Administration / exposure
- Vehicle:
- other: 40 % Lösung in 0.5 % Methylcellulose "ENGLISH" 40 % solution in 0.5 % methylcellulose
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Male: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0 - Clinical signs:
- Signs of toxicity related to dose levels:
Eine Stunde nach der Applikation ausfließen von Kot bei
einem Männchen. 5 Stunden nach der Applikation war davon
nichts mehr zu sehen. Am Tage 3 hatten 2 Männchen und 1
Weibchen Ausfluss von Urin. Das Problem war jedoch am Tage 4
nicht mehr vorhanden. Während der 2 wochen
Beobachtungsperiode wurden keine weiteren klinischen Befunde
festgestellt.
"ENGLISH"
One male rat had fecal soiling of the perineal area with the
hour post dosing, which was resolved 5 hours after dosing.
Two male rats and one female rat had urine soiling of the
perineal area on test day 3. The urine soiling was resolved
by test day 4. There were no other clinical signs identified
during the two-week observation period. - Gross pathology:
- Effects on organs:
Keine Befunde
"ENGLISH"
No treatment related findings
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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