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EC number: 219-941-5 | CAS number: 2579-20-6
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 07 October 2008 to 27 February 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study performed according to GLP and internationally accepted test guidelines.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- > 1 000 g/L
- Conc. based on:
- test mat.
- Remarks on result:
- other: An accurate quantitative result was not obtained because the preliminary test indicated that the water solubility is in excess of 1000 mg/mL. Temperature and pH of the solution were not specified.
- Details on results:
- In a preliminary test, a portion (approximately 500 mg) of the test substance was found to dissolve readily in 0.5 ml of purified water, indicating a solubility of greater than 1000 g/l of water. No further testing was considered necessary. Temperature and pH were not specified
- Conclusions:
- Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The solubility of 1,3-Bis(aminomethyl)cyclohexane was found to be greater than 1000 g/l of water. - Executive summary:
A package of physico-chemical testing including a water solubility test was conducted to determine specific properties of the test substance 1,3-Bis(aminomethyl)cyclohexane. The water solubility test was performed to OECD and EC test guidelines, and in compliance with GLP.
In a preliminary test, a portion (approximately 500 mg) of the test substance was found to dissolve readily in 0.5 ml of purified water, indicating a solubility of greater than 1000 g/l of solvent. No further testing was considered necessary.
The solubility of 1,3-Bis(aminomethyl)cyclohexane was found to be greater than 1000 g/l of water.
Reference
Temperature and pH were not specified as a preliminary test (see results above) indicated further testing was not necessary.
Description of key information
The solubility of 1,3-Bis(aminomethyl)cyclohexane was found to be >1000 g/L of water. However, the key value for water solubility was determined at 100 g/L at 25 °C as this is the advised maximum value in EUSES.
Key value for chemical safety assessment
- Water solubility:
- 100 g/L
- at the temperature of:
- 25 °C
Additional information
A package of physico-chemical testing including a water solubility test was conducted to determine specific properties of the test substance 1,3-Bis(aminomethyl)cyclohexane. The water solubility test was performed to OECD and EC test guidelines, and in compliance with GLP. In a preliminary test, a portion (approximately 500 mg) of the test substance was found to dissolve readily in 0.5 ml of purified water, indicating a solubility of greater than 1000 g/l of water. No further testing was considered necessary. The solubility of 1,3-Bis(aminomethyl)cyclohexane was found to be greater than 1000 g/l of water.
However, the key value for water solubility was determined at 100 g/L at 25 °C as this is the advised maximum value in EUSES.
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