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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 11 OCT 2007 to 5 DEC 2007
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
gas saturation method
Temp.:
25 °C
Vapour pressure:
11 Pa
Remarks on result:
other: measured
Key result
Temp.:
25 °C
Vapour pressure:
10 Pa
Remarks on result:
other: calculated
Temp.:
20 °C
Vapour pressure:
6.3 Pa
Remarks on result:
other: calculated
Temp.:
15 °C
Vapour pressure:
4.1 Pa
Remarks on result:
other: measured
Temp.:
5 °C
Vapour pressure:
1.3 Pa
Remarks on result:
other: measured

The experiments were performed at 25 °C, 15 °C and 5 °C. To ensure saturation control, three different flow rates were used at each temperature.

The experimental results lead to the conclusion that the vapor pressure of the test item DIMETHYL 2-METHYL GLUTARATE is:

11 Pa at 25 °C

4.1 Pa at 15 °C

1.3 Pa at 5 °C

The trapping efficiency of the test item DIMETHYL 2-METHYL GLUTARATE in the first cooling trap was very good. Between 96% and 100% of the test item was trapped in the first cooling trap.

Table 1: Results of the vapor pressure determination of DIMETHYL 2-METHYL GLUTARATE / Trapping efficiency of DIMETHYL 2-METHYL GLUTARATE

 

Column

N°.

Temp.

(°C)

Volume*

V2

(mL)

Amount of the test item in trap 1

(µg)

Amount of test item in trap 2

(µg)

Total amount of test item

(µg)

Vapor pressure

(Pa)

Average vapor pressure (Pa)

Trapping effeciency

1sttrap

(%)

1

2

3

 

25.6

2820

3381

3781

2137.248

2569.199

2895.697

5.052

9.278

12.330

2142.300

2578.476

2908.027

11

11

11

 

11

99.76

99.64

99.58

1

2

3

 

15.45

2801

3408

3870

818.706

1011.861

1125.855

9.328

7.482

11.199

828.034

1019.342

1137.054

4.1

4.1

4.0

 

4.1

98.87

99.27

99.02

1

2

3

 

5.1

4307

5154

5857

427.225

458.720

583.651

16.497

7.638

10.408

443.722

466.358

594.058

1.4

1.2

1.3

 

1.3

96.28

98.36

98.25

 

* corrected volume at test temperature as calculated under “volume correction”

The vapor pressure of DIMETHYL 2-METHYL GLUTARATE at 25 °C and 20 °C were calculated by interpolation from the vapor pressure curve and were calculated to be 10 Pa at 25 °C and 6.3 at 20 °C.

Table 2: Data of the vapor pressure curve for DIMETHYL 2-METHYL GLUTARATE

 

T

(°C)

1/T

(Kelvin)

Ln Pvp

 

25.6

 

0.00335

0.00335

0.00335

2.38

2.39

2.40

 

15.45

 

0.00347

0.00347

0.00347

1.40

1.42

1.40

 

5.1

 

0.00359

0.00359

0.00359

0.31

0.18

0.30

The tabulated results represent rounded-off values obtained by calculations based on the exact

raw data.

Y = b * x + a with Y = ln (Pvp mean in Pa)

x = 1/T (Kelvin)

b = -8612.104 (slope)

a = 31.23 (y-axis intercept)

r2 = 0.9982

Conclusions:
The vapor pressure of DIMETHYL 2-METHYL GLUTARATE was measured at test temperatures of 25 °C, 15 °C and 5 °C and was determined to be 11 Pa at 25 °C, 4.1 Pa at 15 °C, 1.3 Pa at 5 °C.
The vapor pressure of DIMETHYL 2-METHYL GLUTARATE at 25 °C and 20 °C were interpolated from the vapor pressure curve and were calculated to be 10 Pa at 25 °C and 6.3 Pa at 20 °C.
Executive summary:

The vapor pressure of DIMETHYL 2-METHYL GLUTARATE was determined according to the EEC Directive 92/69, A.4 ”Vapour Pressure” (1992) and the OECD guideline No. 104, ”Vapour Pressure” (1995) using the gas saturation method.

The vapor pressure of DIMETHYL 2-METHYL GLUTARATE was measured at test temperatures of 25 °C, 15 °C and 5 °C and was determined to be 11 Pa at 25 °C, 4.1 Pa at 15 °C, 1.3 Pa at 5 °C.

The vapor pressure of DIMETHYL 2-METHYL GLUTARATE at 25 °C and 20 °C were interpolated from the vapor pressure curve and were calculated to be 10 Pa at 25 °C and 6.3 Pa at 20 °C.

Description of key information

The vapor pressure of DIMETHYL 2-METHYL GLUTARATE was measured at test temperatures of 25 °C, 15 °C and 5 °C and was determined to be 11 Pa at 25 °C, 4.1 Pa at 15 °C, 1.3 Pa at 5 °C.

The vapor pressure of DIMETHYL 2-METHYL GLUTARATE at 25 °C and 20 °C were interpolated from the vapor pressure curve and were calculated to be 10 Pa at 25 °C and 6.3 Pa at 20 °C.


Key value for chemical safety assessment

Vapour pressure:
10 Pa
at the temperature of:
25 °C

Additional information

One experimental study, scored as Klimisch 1, is available (Badt-Tognucci A., 2007) and selected as a key study.