Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-838-7 | CAS number: 111-14-8
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
Description of key information
An OECD 208 GLP study was conducted on 6 plant species from 6 different families, respecting the ratio 4 dicotyledonous for 2 monocotyledonous. No biologically significant effect were seen on emergence, survival or phytotoxicity. However, heptanoic acid reduced the growth of 4 species. Brassica rapa was by far the most sensitive species. The EC10 considered for risk assessment is 1.2 mg/kg soil dry weight.
Key value for chemical safety assessment
- Long-term EC10, LC10 or NOEC for terrestrial plants:
- 1.2 mg/kg soil dw
Additional information
The long-term toxicity of heptanoic acid to plants was investigated through an OECD 208 GLP study and using 6 different plant species (4 dicotyledonous and 2 monocotyledonous) from 6 different plant families representing an area as wide as possible across the phylogenetic distribution of the plant kingdom. The 6 species were Brassica rapa (Brassicaceae), Lactuca sativa (Asteraceae), Beta vulgaris (Amaranthaceae), Glycine max (Fabaceae), Allium cepa (Liliaceae) and Lolium perenne (Poaceae). The nominal tested concentrations tested were 0 ; 0.3 ; 1 ; 3 ; 10 ; 30 ; 100 mg/kg soil (dry weight) for all plant species. Thirty seeds per treatment and per species were used. The experiment for the dicotyledonous species was carried out in decaplicate (10 independent pots per treatment) while it was carried out in hexaplicate for the monocotyledonous plants. During the 21 days incubation, seedling emergence, plant mortality and phytotoxicity were recorded. After 21 days incubation (end of the test), the dry weight of shoot per pot was measured. There were no biologically significant effect of heptanoic acid on emergence, survival and phytotoxicity in any species. There were however an inhibitory effect of heptanoic acid on plant growth (as measured by shoot dry weight) on Beta vulgaris, Brassica rapa, Lactuca sativa and Lolium perenne. The most sensitive species was by far Brassica rapa, with an EC10 of 1.2 mg/kg soil dry weight (based on initially measured concentrations in soil).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
