Registration Dossier
Registration Dossier
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EC number: 700-400-1 | CAS number: 42831-50-5
Additional information on environmental fate and behaviour
Administrative data
- Endpoint:
- additional information on environmental fate and behaviour
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The partition coefficient was obtained by the shake flask method according to the EU Method A.8.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 2000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: EU Method A8.
- Principles of method if other than guideline:
- For the determination of the partition coefficient of 5-Methylisoxazole-4-carboxylic acid, the HPLCmethod was used.
The calibration of the method based on six reference substances with LogP values ranged from 0.3 to 1.8. - GLP compliance:
- yes
Test material
- Reference substance name:
- 5-methyl-1,2-oxazole-4-carboxylic acid
- EC Number:
- 700-400-1
- Cas Number:
- 42831-50-5
- Molecular formula:
- C5H5NO3
- IUPAC Name:
- 5-methyl-1,2-oxazole-4-carboxylic acid
Constituent 1
Results and discussion
Any other information on results incl. tables
The calibration reads logk=0.0014 +0.686*LogP with a correlation coefficient of 0.983.
The test article showed a signal at 9.18min. The corresponding LogP value of 5 -Methylisoxazole-4 -carboxylic acid is 0.54.
Applicant's summary and conclusion
- Conclusions:
- 5 -Methylisoxazole-4 -carboxylic acid LogP=0.54.
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