Registration Dossier
Registration Dossier
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EC number: 215-277-5 | CAS number: 1317-61-9
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: exposure not quantified
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 978
Materials and methods
- Study type:
- clinical case study
- Principles of method if other than guideline:
- Chest radiograph and physical examination
Test material
- Reference substance name:
- Triiron tetraoxide
- EC Number:
- 215-277-5
- EC Name:
- Triiron tetraoxide
- Cas Number:
- 1317-61-9
- Molecular formula:
- Fe3O4
- IUPAC Name:
- Iron oxide
- Details on test material:
- Inhaled material was analysed and found to consist almost entirely of iron with a negligible silica content and no impurities
Constituent 1
Method
- Subjects:
- 40-year old male with an occupational history of working for nine years in a "Ball Mill" which washed and pulverised magnetite
Results and discussion
- Clinical signs:
- cough, abnormal chest radiograph
Applicant's summary and conclusion
- Executive summary:
A subject is described who was exposed to fine particles of magnetite (Fe3O4). His
chest radiograph demonstrated the presence of multiple small rounded opacities;
however, the lung function remained unaffected
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