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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
6 - 21 Apr 2009
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report date:
2009

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method B.1 tris (Acute Oral Toxicity - Acute Toxic Class Method)
Version / remarks:
OECD 423
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
sukls28108/2009
Test type:
acute toxic class method
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Reaction products of acetic acid and acetylferrocene and butan-1-ol and 2-methylpropan-1-ol and propan-1-ol and propan-2-ol
EC Number:
700-283-7
Molecular formula:
Exact molecular formula is not known as it is a reaction mass. Empiric formula: C5H5FeC5H4COCmHn
IUPAC Name:
Reaction products of acetic acid and acetylferrocene and butan-1-ol and 2-methylpropan-1-ol and propan-1-ol and propan-2-ol
Details on test material:
According to INQ-C-0000036278-61-01, INQ-C-0000036386-62-01, and INQ_RESULT_INQ-C-0000036417-65-01 from ECHA, identification of a substance has been changed to UVCB substance. Name of the substance on the study results is the old name (reaction mass of butan-1-ol and propan-2-ol, ReduxCo), however these reports should be regarded valid as all studies were performed on the substance that is being registered - ReduxCo.

Test animals

Species:
rat
Strain:
Wistar
Sex:
female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
other: aqua pro injectione
Doses:
the single volume of administered suspension was 1 ml/100 g of animal body weight
No. of animals per sex per dose:
two groups of 3 females - application distance 24 hours
Control animals:
not specified

Results and discussion

Effect levels
Sex:
female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw

Any other information on results incl. tables

The test substance administered at the dose of 2000 mg/kg caused no death of animals.Clinical signs of intoxication were observed in all animals at 30 miniutes and 3 hours after application. In the morning of the second day no clinical signs of intoxication were detected in all animals. No pathologic macroscopic changes were diagnosed during pathological examination in all animals.

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
According to the study results the value of LD50 of the test substance for female rats is higher than 2000 mg/kg of body weight.
Executive summary:

Based on the test results and according to the EC criteria for classification and labelling requirements for dangerous substances and preaprationd the test substance ReduxCo did not fall into any of quoted categories of toxicity and has no obligatory labelling requirements in this respect.