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Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

A literature data shows the half-life time of the substance in soil is 67 days at 22°C.

Key value for chemical safety assessment

Half-life in soil:
67 d
at the temperature of:
22 °C

Additional information

CO2 evolution test, FDA-TAD 3.12, GLP [[i]]
mean aerobic DT50 (primary) = 67 days at 22 °C
mean aerobic DT50 (mineralisation) = 925 days


























Soil type



Degradation, 72 days



DT50



Clay loam



42.2 %



79 days



Silty loam



53.5 %



62 days



Loam



55.6 %



61 days



Metabolites after 72 days: 14 quantifiable compounds in all soils, with 8-α-hydroxydoramectin in silt loam (12.7 – 13.8 %) and loam (7.09 %).


[i]         Fernando, T. R. (1993). Aerobic Biodegradation of Doramectin in Soil. Battelle Columbus Operations, USA, study SC920011.
ZRD-STU-019206