Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 941-489-9 | CAS number: -
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- other: trend analysis
- Adequacy of study:
- key study
- Study period:
- 2014
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: This study is classified as reliable with restrictions because it is an acceptable and reliable study carried out by OECD ToolBox v.3.2.0. Meets generally accepted scientific principles, acceptable for assessment.
Data source
Reference
- Reference Type:
- other: software
- Title:
- QSAR ToolBox 3.2.0.103
- Author:
- OECD
- Year:
- 2 014
- Bibliographic source:
- http://www.oecd.org/env/ehs/risk-assessment/theoecdqsartoolbox.htm
Materials and methods
- Principles of method if other than guideline:
- Predicted from category members using trend analysis.
- GLP compliance:
- not specified
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 6β-fluoro-16α,17,21-trihydroxypregna-1,4,9(11)-triene-3,20-dione 21-acetate
- EC Number:
- 262-484-1
- EC Name:
- 6β-fluoro-16α,17,21-trihydroxypregna-1,4,9(11)-triene-3,20-dione 21-acetate
- Cas Number:
- 60864-44-0
- IUPAC Name:
- 6-fluoro-16,17-dihydroxy-3,20-dioxopregna-1,4,9(11)-trien-21-yl acetate
- Reference substance name:
- 9-fluoro-11β-hydroxy-16α,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione
- EC Number:
- 218-368-8
- EC Name:
- 9-fluoro-11β-hydroxy-16α,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione
- Cas Number:
- 2135-14-0
- IUPAC Name:
- 6b-acetyl-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- Reference substance name:
- 1597-78-0
- EC Number:
- 605-189-9
- Cas Number:
- 1597-78-0
- IUPAC Name:
- 1597-78-0
- Reference substance name:
- 6α-fluoro-17,21-dihydroxy-16α-methylpregna-4,9(11)-diene-3,20-dione 21-acetate
- EC Number:
- 217-536-8
- EC Name:
- 6α-fluoro-17,21-dihydroxy-16α-methylpregna-4,9(11)-diene-3,20-dione 21-acetate
- Cas Number:
- 1881-07-8
- IUPAC Name:
- 6-fluoro-17-hydroxy-16-methyl-3,20-dioxopregna-4,9(11)-dien-21-yl acetate
- Reference substance name:
- 9-fluoro-11β,17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione 17-acetate
- EC Number:
- 223-270-3
- EC Name:
- 9-fluoro-11β,17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione 17-acetate
- Cas Number:
- 3801-06-7
- IUPAC Name:
- 9-fluoro-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl acetate
- Reference substance name:
- 6677-98-1
- Cas Number:
- 6677-98-1
- IUPAC Name:
- 6677-98-1
- Reference substance name:
- (20R)-11β,17,20,21-tetrahydroxy-6α-methylpregna-1,4-dien-3-one 21-acetate
- EC Number:
- 300-818-0
- EC Name:
- (20R)-11β,17,20,21-tetrahydroxy-6α-methylpregna-1,4-dien-3-one 21-acetate
- Cas Number:
- 93963-74-7
- IUPAC Name:
- 11,17,20-trihydroxy-6-methyl-3-oxopregna-1,4-dien-21-yl acetate
- Reference substance name:
- 3-β-acetoxy-14-hydroxy-5-β,14-β-card-20(22)-enolide
- EC Number:
- 212-363-4
- EC Name:
- 3-β-acetoxy-14-hydroxy-5-β,14-β-card-20(22)-enolide
- Cas Number:
- 808-19-5
- IUPAC Name:
- 3-acetoxy-14-hydroxycard-20(22)-enolide
- Reference substance name:
- Methylprednisolone 21-acetate
- EC Number:
- 200-171-3
- EC Name:
- Methylprednisolone 21-acetate
- Cas Number:
- 53-36-1
- IUPAC Name:
- 11,17-dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate
- Reference substance name:
- 6α-fluoro-17,21-dihydroxy-16α-methylpregna-1,4,9(11)-triene-3,20-dione 21-acetate
- EC Number:
- 243-315-0
- EC Name:
- 6α-fluoro-17,21-dihydroxy-16α-methylpregna-1,4,9(11)-triene-3,20-dione 21-acetate
- Cas Number:
- 19788-77-3
- IUPAC Name:
- 6-fluoro-17-hydroxy-16-methyl-3,20-dioxopregna-1,4,9(11)-trien-21-yl acetate
Constituent 1
Constituent 2
Constituent 3
Constituent 4
Constituent 5
Constituent 6
Constituent 7
Constituent 8
Constituent 9
Constituent 10
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 2.66
- Remarks on result:
- other: Calculated by OECD Toolbox
Any other information on results incl. tables
The target chemical FALLS within applicability domain of the method.
Applicant's summary and conclusion
- Conclusions:
- By calculation with a reliable software a partition coefficient of 2.66 has been estimated.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
