Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 941-489-9 | CAS number: -
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- other: trend analysis
- Adequacy of study:
- key study
- Study period:
- 2014
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Solubility has been obtained by trend analysis from category members using the OECD Toolbox v.3.2.
Data source
Reference
- Reference Type:
- other: software
- Title:
- QSAR ToolBox 3.2.0.103
- Author:
- OECD
- Year:
- 2 014
- Bibliographic source:
- http://www.oecd.org/env/ehs/risk-assessment/theoecdqsartoolbox.htm
Materials and methods
- Principles of method if other than guideline:
- Water solybility of the target chemical is predicted from category members using trend analysis based on 370 values within the range 0.0306 - 2.84E+05 mg/L from 370 category members. Category members are single chemicals or mixtures and are selected based on the profile of the target chemical. Only chemicals having experimental data are used in the category.
- Type of method:
- other: trend analysis
Test material
- Reference substance name:
- 11β,21-dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate
- EC Number:
- 221-250-9
- EC Name:
- 11β,21-dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate
- Cas Number:
- 3044-42-6
- IUPAC Name:
- 11-hydroxy-3,20-dioxopregna-1,4,16-trien-21-yl acetate
- Reference substance name:
- Prednisolamate
- EC Number:
- 227-064-4
- EC Name:
- Prednisolamate
- Cas Number:
- 5626-34-6
- IUPAC Name:
- 11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl N,N-diethylglycinate
- Reference substance name:
- 9-fluoro-11β,21-dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate
- EC Number:
- 215-006-0
- EC Name:
- 9-fluoro-11β,21-dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate
- Cas Number:
- 1250-85-7
- IUPAC Name:
- 9-fluoro-11-hydroxy-3,20-dioxopregna-1,4,16-trien-21-yl acetate
- Reference substance name:
- 75883-07-7
- Cas Number:
- 75883-07-7
- IUPAC Name:
- 75883-07-7
- Reference substance name:
- Amcinafal
- EC Number:
- 223-497-8
- EC Name:
- Amcinafal
- Cas Number:
- 3924-70-7
- IUPAC Name:
- 8,8-diethyl-4b-fluoro-6b-glycoloyl-5-hydroxy-4a,6a-dimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- Reference substance name:
- 6α,9-difluoro-11β,21-dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate
- EC Number:
- 219-040-7
- EC Name:
- 6α,9-difluoro-11β,21-dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate
- Cas Number:
- 2326-26-3
- IUPAC Name:
- 6,9-difluoro-11-hydroxy-3,20-dioxopregna-1,4,16-trien-21-yl acetate
- Reference substance name:
- 9β,11β-epoxy-17,21-dihydroxypregna-1,4-diene-3,20-dione 21-acetate
- EC Number:
- 254-079-3
- EC Name:
- 9β,11β-epoxy-17,21-dihydroxypregna-1,4-diene-3,20-dione 21-acetate
- Cas Number:
- 38680-83-0
- IUPAC Name:
- 17-hydroxy-3,20-dioxo-9,11-epoxypregna-1,4-dien-21-yl acetate
- Reference substance name:
- 5α,6α-epoxy-3β,17-dihydroxy-16α-methylpregnan-20-one 3-acetate
- EC Number:
- 220-671-5
- EC Name:
- 5α,6α-epoxy-3β,17-dihydroxy-16α-methylpregnan-20-one 3-acetate
- Cas Number:
- 2857-83-2
- IUPAC Name:
- 17-hydroxy-16-methyl-20-oxo-5,6-epoxypregnan-3-yl acetate
- Reference substance name:
- 9-fluoro-11β,21-dihydroxy-16α,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione 21-acetate
- EC Number:
- 223-388-5
- EC Name:
- 9-fluoro-11β,21-dihydroxy-16α,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione 21-acetate
- Cas Number:
- 3870-07-3
- IUPAC Name:
- 2-(4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl)-2-oxoethyl acetate
- Reference substance name:
- 4351-59-1
- Cas Number:
- 4351-59-1
- IUPAC Name:
- 4351-59-1
Constituent 1
Constituent 2
Constituent 3
Constituent 4
Constituent 5
Constituent 6
Constituent 7
Constituent 8
Constituent 9
Constituent 10
Results and discussion
Water solubility
- Water solubility:
- 18.7 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: Calculated by OECD Toolbox v.3.2
Any other information on results incl. tables
The target chemical FALLS within applicability domain of the method.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
By this trend analysis a water solubility of 18.7 mg/L has been calculated.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
