Registration Dossier

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vitro / ex vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2020

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 492 (Reconstructed Human Cornea-like Epithelium (RhCE) Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Lithium 12-hydroxystearate
EC Number:
231-536-5
EC Name:
Lithium 12-hydroxystearate
Cas Number:
7620-77-1
Molecular formula:
C18H36O3.Li
IUPAC Name:
lithium 12-hydroxyoctadecanoate
Test material form:
solid

Results and discussion

In vitro

Results
Remarks on result:
other: Test currently ongoing
Remarks:
Test currently ongoing

Applicant's summary and conclusion

Interpretation of results:
other: Test currently ongoing
Conclusions:
The in vitro eye irritation potential of lithium 12-hydroxystearate was determined to be
Executive summary:

The in vitro eye irritation potential of lithium 12-hydroxystearate was tested in a reconstructed human cornea-like epithelium test (RhCE) was determined to be