Registration Dossier
Registration Dossier
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EC number: 205-503-0 | CAS number: 141-82-2
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- Research document comparing vapour pressure of low molecular weight dicarboxylic acids
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Evaporating single aerosol particles in an electrodynamic balance (EDB)
- GLP compliance:
- no
- Key result
- Test no.:
- #1
- Temp.:
- ca. 25 °C
- Vapour pressure:
- ca. 0 Pa
- Conclusions:
- Low vapour pressure, below limits significant for exposure by inhalation and not relevant for environmental partitioning.
- Executive summary:
Using EPISuite, the vapour pressure is estimated to be ca 0.1 Pa at 25 C. This is in line with modelled figures cited for oxalic and succinic acid, although it appears that the published figures are themselves based on calculation methods and not laboratory testing.
The key reference used that provides figures for measured vapour pressure and these appear much lower than those predicted. The figures for oxalic, malonic and succinic acid respectively are 0.00025, 0.00006 and 0.000008 Pa, with correlation with molecular weights.
Reference
Description of key information
Low vapour pressure, below limits significant for exposure by inhalation and not relevant for environmental partitioning.
Using EPISuite, the vapour pressure is estimated to be ca 0.1 Pa at 25 C. This is in line with modelled figures cited for oxalic and succinic acid, although it appears that the published figures are themselves based on calculation methods and not laboratory testing.
The key reference used that provides figures for measured vapour pressure and these appear much lower than those predicted. The figures for oxalic, malonic and succinic acid respectively are 0.00025, 0.00006 and 0.000008 Pa, with correlation with molecular weights.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 25 °C
Additional information
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