Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other: Predicted data
Title:
Unnamed
Year:
2016

Materials and methods

Test guideline
Guideline:
other: REACH guidance on QSARs R.6, May/July2008
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3-Hydroxy-2-[(2E)-2-(6-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)ethyl]-2-methylcyclopentanone
EC Number:
613-827-2
Cas Number:
6563-82-2
Molecular formula:
C19H24O3
IUPAC Name:
3-Hydroxy-2-[(2E)-2-(6-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)ethyl]-2-methylcyclopentanone

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
3.92 mg/L
Nominal / measured:
estimated
Remarks on result:
other: Database: Aquatic Japan MoE (Daphnia Magna)

Applicant's summary and conclusion

Conclusions:
According to (Q)SAR modell: QSAR Toolbox, the predicted value indicated that methyl-secoolon is hazardous to the aquatic invertebrates (Daphnia magna). The result meets the requirement of Aquatic Acute Category 2.