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EC number: 276-763-0 | CAS number: 72676-55-2
There were no deaths. No signs of systemic toxicity were noted in the test or control animals during the test. Pale yellow colored residual test item on the ears was noted on all the test mice: Day 1 (post dose) and Days 2 to 4 at a concentration of 50% w/w in dimethyl formamide; Days 1, 2 and 3 (post dose) at a concentration of 25% w/w in dimethyl formamide; and Days 2 and 3 (post dose) at a concentration of 10% w/w in dimethyl formamide.
In a LLNA (OECD 429), conducted according to GLP, 5,5'-Dithiodi-1,3,4-thiadiazole-2(3H)-thione was tested at 10%, 25% and 50% concentration in dimethyl formamide, and resulted in a positive response in mice, with a stimulation index of 7.71, 10.03 and 6.11, respectively. 5,5'-Dithiodi-1,3,4-thiadiazole-2(3H)-thione is therefore considered a skin sensitiser. No EC3 could be determined in the absence of dose-response.
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