Silicon boride oxide

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Study period:

April 2012

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study performed according to OECD Guideline and to Good Laboratory Practice

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2012

Report date:

2012

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

Boron silicate

EC Number:

603-157-9

Cas Number:

12676-29-8

Molecular formula:

H7 B7 Si57 O128

IUPAC Name:

Boron silicate

Test material form:

solid: particulate/powder

Remarks:

migrated information: powder

Details on test material:

Purity. > 90%
Lot: 97731275L0

Sampling and analysis

Analytical monitoring:

yes

Test solutions

Vehicle:

no

Test organisms

Test organisms (species):

Daphnia magna

Details on test organisms:

Daphnia magna, not being the first brood progeny, was the test species. The test organisms were 6 to 24 hours old at the start of the test.
All organisms used for a particular test originated from cultures established from the samehealthy stock of daphnia.

Study design

Test type:

static

Water media type:

freshwater

Limit test:

yes

Total exposure duration:

48 h

Test conditions

Test temperature:

20.8 - 21.5 °C

pH:

7.31 - 7.53

Dissolved oxygen:

88% to 101% of air saturation

Nominal and measured concentrations:

150 mg/L (nominal)
2.99 mg/L (measured)

Details on test conditions:

Test solutions at different concentrations were prepared by directly adding appropriate amounts of the test substance to the growth medium and
then facilitating its dispersion by ultrasonication for 30 min. After this the test substance preparations were stirred for 24 hours and then divided to the breakers with 50mL each. After a period of one hour for precipitation of the test substance when the test solutions were visually clear, the test
organisms were inserted.

Reference substance (positive control):

yes

Remarks:

Potasssium dichromate

Results and discussion

Effect concentrations

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

> 150 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Results with reference substance (positive control):

24-h EC50: 0.65 mg/L