Reaction productReaction product of 1,1´-Methylenebis(4-substituted cyclohexane), [2-(substitutedmethyl)-3-prop-2-enoyloxy-2-(prop-2-enoyloxymethyl)propyl] prop-2-enoate and [3-prop-2-substituted-2,2-bis(prop-2-enoyloxymethyl)propyl] prop-2-enoate

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

03 January 2012- 19 March 2012

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study has been performed according to OECD and EC guidelines and according to the principles of GLP.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2012

Report date:

2012

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

(2008)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

(1995)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Test material

Test material information

Constituent 1

Details on test material:

- Physical state: Clear colourless/slightly yellow, sticky resin
- Stability under test conditions: Stable
- Storage condition of test material: At room temperature protected from light
-Stability at higher temperatures: Maximum 1 month at 50°C
- General information: Avoid heat, direct sunlight, acid and base

Results and discussion

Water solubility

Water solubility:

g/L

Temp.:

20 °C

Details on results:

Preliminary test:
The content of test substance dissolved in the water sample was 7.98 mg/l after a first centrifugation step and 8.13 mg/l after a second centrifugation step. The response in the blank expressed as test substance concentration was 2.38 mg/l after a first centrifugation step and 3.92 mg/l after a second centrifugation step.

Main study:
After 72 hours of stirring, the test substance in the mixture at a loading rate of 5 mg/l had completely dissolved. All other mixtures contained undissolved material. Based on this visual observation, water solubility was expected to be <10 mg/l. The results for the samples at loading rates of 5, 10, 100 and 1000 mg/l taken at 24, 48 and 72 hours after centrifugation are given in the table below. The concentrations in the test samples were corrected for the mean response in the blank water mixture.

Any other information on results incl. tables

Table: Water solubility results

 

Loading rate   [mg TS/l]	Stirring time [hours]	Analysed concentration [mg C/l]	Analysed concentration [mg TS/l]	Analysed concentration corrected^1 [mg TS/l]	Mean analysed concentration [mg TS/l]	pH
0	72	0.744	1.13
	72	0.567	0.861
	72	0.480	0.729
5	24	0.707	1.07	0.166	0.7	7.2
	48	0.907	1.38	0.470		7.2
	72	1.60	2.42	1.52		7.3
10	24	1.52	2.31	1.40	1.6	7.3
	48	1.04	1.58	0.670		7.3
	72	2.43	3.68	2.78		7.2
100	24	5.44	8.24	7.34	8.0	7.1
	48	6.57	9.97	9.06		7.1
	72	5.64	8.56	7.65		7.1
1000	24	12.3	18.7	17.8	66.2	7.2
	48	37.6	57.1	56.2		7.2
	72	82.8	126	125		7.1

¹            Corrected for the mean of the blanks.

TS          Test substance.

Applicant's summary and conclusion

Conclusions:

Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L) < 10 mg/L
The water solubility of the test substance at 20°C and pH 7.1-7.3 is < 10 mg/L.