Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Acute toxicity oral:  supporting study:  results from a publication leading to the conclusion that the LD50 = 15 mg/kg bw (rat).
Acute toxicity inhalation: supporting studies: results from different publications leading to the conclusion that LC50 is 100 mg/m³ air and 25-50 ppm (4h) (rat).
Acute toxicity dermal: supporting study: result from a publication, leading to the conclusion that LD50 is 14mg/kg (guinea pig)
Acute toxicity other routes: supporting studies: results from different publications leading to the conclusion that LD50= 3.5 mg/kg i.p. in rats and 4 mg/kg bw i.p. in mice, and that ethyleneimine causes renal papillary necrosis.

Key value for chemical safety assessment

Additional information

Acute toxicity oral: supporting study: results from a publication leading to the conclusion that the LD50 = 15 mg/kg bw (rat).

Acute toxicity inhalation: supporting studies: results from different publications leading to the conclusion that LC50 is 100 mg/m³ air and 25-50 ppm (4h) (rat).

Acute toxicity dermal: supporting study: result from a publication, leading to the conclusion that LD50 is 14 mg/kg (guinea pig)

Acute toxicity other routes: supporting studies: results from different publications leading to the conclusion that LD50= 3.5 mg/kg i.p. in rats and 4 mg/kg bw i.p. in mice, and that ethyleneimine causes renal papillary necrosis.

Justification for classification or non-classification

Harmonised classification included in Part 3 of Annex VI of CLP Regulation:

Acute oral toxicity Category 2* (minimum classification)

Acute dermal toxicity Category 1

Acute inhalation toxicity Category 2* (minimum classification)