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EC number: - | CAS number: -
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 October 2011- 31 January 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study has been performed according to OECD and EC guidelines and according to the principles of GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Version / remarks:
- (2004)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Version / remarks:
- (2008)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Type:
- log Pow
- Partition coefficient:
- 6.1
- Temp.:
- 25 °C
- pH:
- 7
- Remarks on result:
- other: Peak 1 (area of 64 %)
- Type:
- log Pow
- Partition coefficient:
- 6.8
- Temp.:
- 25 °C
- pH:
- 7
- Remarks on result:
- other: Peak 2 (area of 36 %)
- Details on results:
- In the HPLC chromatogram of the test solution, two test substance peaks were observed (see attached Figure). The equation of the regression line (see attached Figure) was: log k` = 0.264 x log Pow – 0.393 (r = 0.993, n = 12).
- Conclusions:
- The log Pow of FAT 41043/A was determined to be 6.1/6.8 (two components) by the HPLC method.
Reference
Description of key information
The log Pow of FAT 41043/A was determined to be 6.1/6.8 by the HPLC method (EC A.8 and OECD 117).
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 6.1
- at the temperature of:
- 25 °C
Additional information
Two isomers
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