Registration Dossier
Registration Dossier
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EC number: 210-275-0 | CAS number: 611-70-1
Endpoint summary
Administrative data
Description of key information
The median lethal dose (LD50) was 2167 mg/kg for both sexes
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Additional information
Isobutyrophenone was tested for acute toxicity in rats after oral administration. Mortality occurred 23 hours after treatment and on day 3 of the study.The median lethal doses(LD50),determined by logit analysis, after an observation period of 14 days, were:
- 2167 (1718 - 2732) mg/kg for males and females;
- > 2000 mg/kg for males; and
- 1946 (1734 - 2185) mg/kg for females.
Justification for classification or non-classification
There are conclusive but not sufficient data for classification of Isobutyrophenone with regard to acute oral toxicity.
Isobutyrophenone is not classified for this endpoint in accordance to Directive 67/548/EEC or the CLP Regulation (EC) No 1272/2008.
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