Registration Dossier
Registration Dossier
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EC number: 203-116-1 | CAS number: 103-48-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of the test substance to the unicellular freshwater green alga Pseudokirchneriella subcapitata was determined according to the principles of OECD 201 (2011) and Council Regulation (EC) No 761/2009 C.3 at the test facility. After 72 hours the NOEC was determined to be 1.64 mg/L, the ErC10 was determined to be 4.86 mg/L and the ErC50 was determined to be 8.33 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 8.33 mg/L
- EC10 or NOEC for freshwater algae:
- 4.86 mg/L
Additional information
The toxicity of the test substance to the unicellular freshwater green alga Pseudokirchneriella subcapitata was determined according to the principles of OECD 201 (2011) and Council Regulation (EC) No 761/2009 C.3 at the test facility under GLP conditions. Five concentrations were tested in a geometrical series with a dilution factor of 3.16, The nominal concentrations were: 0.20, 0.632, 2.00, 6.32 and 20.0 mg/L. The test media were clear throughout the test period. The concentrations of the test item in all test concentrations and the control were analytically verified by HPLC-DAD at the start and the end of exposure. The measured concentrations of the test substance in the fresh media (0 h) were determined to be between 99 and 103 % of the nominal values. The measured concentrations in the old media (72 h) containing algae were in the range of 67 to 87 % of the nominal values. All effect values given are based on the geometric mean measured test item concentrations. After 72 hours the NOEC was determined to be 1.64 mg/L, the ErC10 was determined to be 4.86 mg/L and the ErC50 was determined to be 8.33 mg/L.
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