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EC number: 215-158-8 | CAS number: 1308-14-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
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- Density
- Particle size distribution (Granulometry)
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- Nanomaterial specific surface area
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- Nanomaterial surface chemistry
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- Nanomaterial pour density
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- Endpoint summary
- Stability
- Biodegradation
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- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 96 hours
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Qualifier:
- according to guideline
- Guideline:
- other: Protocol for bioassessment of hazardous waste sites. EPA-600/2-83-05
- Principles of method if other than guideline:
- 96 hours exposure period
- GLP compliance:
- no
- Specific details on test material used for the study:
- Chromium chloride used as a reference, but analysis and result all expressed as Cr3+
- Analytical monitoring:
- yes
- Details on sampling:
- Detaills not described
- Vehicle:
- no
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- Algal cells (10,OOO cells/ml) were exposed to the test solutions for 96 h. Algae cultured in algal assay medium served as the controls.
- Test type:
- static
- Water media type:
- freshwater
- Remarks:
- Natural water, contaminated with Chromium
- Limit test:
- no
- Total exposure duration:
- 96 h
- Remarks on exposure duration:
- This exceeds normal guidelines for 72 hour exposure. This should not greatly impact on the results in since this is a satable inorganic substance.
- pH:
- Samples on which algal assays were performed were adjusted with 0.1 N NaOH, as necessary, to a final pH that ranged from 5.6 to 8.9
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.3 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- element
- Remarks:
- chromium
- Basis for effect:
- biomass
- Key result
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- ca. 0.6 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- other: Cr (OH)3
- Basis for effect:
- biomass
- Details on results:
- The research using different contaminated waters resulted in an EC50 range of 0.229 - 0.360 mg/l with a mean of 0.265 mg/l CrThese have been rounded to 0.3 mg/l Cr.
- Reported statistics and error estimates:
- Linear regression analysis [9] was used to calculate the mean inhibitory concentrations (EC50) related to measured chromium concentrations.The difference in yields between the control and test flasks was calculated and reported as percent inhibition.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Water from a number of contaminated sources was assessed for toxicity and a relatively consistant EC50 determined of ca 0.3 mg/l CrThis equates to an estimated EC50 0.6 mg/l Cr (OH)3
- Executive summary:
Peer reviewed research using scientifically valid methods determined the inhibitory concentrations of Cr3+ to algea
Estimed EC50 for Cr (OH)3 is 0.6 mg/l.
Reference
Description of key information
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.6 mg/L
Additional information
Based on Cr3+ EC50 0.3 mg/l
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