Tetrylammonium bromide

Density

Link to relevant study record(s)

Reference

Endpoint:

density

Remarks:

density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

06-02-2017 – 06-02-2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental test result performed using standard OECD test guidelines

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Principles of method if other than guideline:

The density is calculated from the difference in weight between the full and empty pycnometer and its volume

GLP compliance:

no

Type of method:

pycnometer method

Specific details on test material used for the study:

- Name of test material : Tetrylammonium bromide
- IUPAC name: N,N,N-triethylethanaminium b romide
- Molecular formula: C8 H20 N.Br
- Molecular weight: 210.157 g/mol
- Smiles notation: [N+](CC)(CC)(CC)CC.[BrH-]
- InChl : 1S/C8H20N.BrH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1
- Substance type: Organic
- Physical state: Solid crystalline powder (white)
- Purity: 99.23%

Key result

Type:

pour density

Density:

0.625 g/cm³

Temp.:

28.1 °C

Remarks on result:

other: at 977.9 hPa pressure

Key result

Type:

tap density

Density:

0.714 g/cm³

Temp.:

28.1 °C

Remarks on result:

other: at 977.9 hPa pressure

Method Details		Observations
Guideline	OECD 109	1^stReading	2^ndReading
Method	Test methods: Pour density and tapped density of powders” recommended in The International Pharmacopoeia, Fourth Edition, 2014
Principle of method	Pour Density:It is the ratio of known weight of test item and its volume in graduated glass cylinder. Tap Density: It is the difference between the volume of test item measured before & after tapping in the graduated glass cylinder.
Test temperature (°C)		28.1 °C	28.1 °C
Atmospheric pressure (in hPa)		978.3	977.6
Weight of test item(m)		10.002	10.001
Volume of measuring cylinder; readability in g		50ml ; 1 ml	50 ml; 1ml
Volume of test item without tapping (V)		16 ml	16 ml
Volume of test item after tapping ( V1)	After 10 tapping	15 ml	15 ml
	After 50 tapping	14 ml	14 ml
	After 100 tapping	14 ml	14 ml
	After 250 tapping	-	-
	After 500 tapping	-	-
	After 750 tapping	-	-

 

CALCULATIONS:

By Pour Density and Tapped Density Method:

Parameters	Details	Calculated values		Average Density
		1st Calculation	2nd Calculation
Pour Density of test Item (g/cm³)	m/v	0.6251	0.6250	0.6250
Tap density of test Item (g/cm³)	m/v	0.7144	0.7143	0.7143

Conclusions:

The mean pour density and mean tapped density of Tetrylammonium bromide (CAS No. 71-91-0) was found to be 0.6250 g/cm³ and 0.7143 g/cm³ at 28.1 °C and 977.9 hPa.

Executive summary:

The density of test item Tetrylammonium bromide (CAS No. 71-91-0) was determined following OECD Guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition, 2014. The mean pour density and mean tapped density of test item was found to be 0.6250 g/cm³ and 0.7143 g/cm³ at 28.1 °C and 977.9 hPa.

Description of key information

The mean pour density and mean tapped density of Tetrylammonium bromide (CAS No. 71-91-0) was found to be 0.6250 g/cm³ and 0.7143 g/cm³ at 28.1 °C and 977.9 hPa.

Key value for chemical safety assessment

Relative density at 20C:

0.714

Additional information

The density of test item Tetrylammonium bromide (CAS No. 71-91-0) was determined following OECD Guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition, 2014. The mean pour density and mean tapped density of test item was found to be 0.6250 g/cm³ and 0.7143 g/cm³ at 28.1 °C and 977.9 hPa.

Other supporting data from authoritative database and handbook, also determined the density of chemical Tetrylammonium bromide (CAS No. 71-91-0) as 1.397 g/cm3 at 20 degree C.