Iron digluconate

Density

Link to relevant study record(s)

Reference

Endpoint:

bulk density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

23 January 2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

comparable to guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

yes

Remarks:

The modification being a 25 ml graduated cylinder was used instead of a pycnometer.

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Principles of method if other than guideline:

- Short description of test conditions: The analysis was performed accrding to to methods given above. The deviation is the use of a 25 ml graduated cylinder instead of a pycnometer. The sample was added to the 25 ml mark of the graduated cylinder and was vibrated to pack the sample in the graduate. Material was added until a steady volume of 25 ml was read. The sample was then weighted. As the sample varied in particle size, three well mixed aliquots were taken.

GLP compliance:

not specified

Type of method:

air comparison pycnometer (for solids)

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material:

Commercial Name: Sourscav
Lot number: 20131012
Manufacturer: Polytec International Ltd.

Key result

Type:

bulk density

Density:

ca. 0.79 g/cm³

Temp.:

21 °C

The average density is 0.79 g/cm³ at 21°C. Analysis was performed in triplicates (see table).

Density Results  Sample Trial Measured Bulk density (g/cm^3)  Sample Temperature (°C)   1  0.80 21   2  0.79 21   3  0.79  21

Conclusions:

The average density value of 0.79 g/cm3 at 21°C was determined in a reliable study conducted according to an appropriate standard test methods.

Description of key information

EU Method A.3 (relative density)/OECD Guideline 109 (Density of liquids and solids)
 The average density is 0.79 g/cm3 at 21°C.

Key value for chemical safety assessment

Relative density at 20C:

0.79

Additional information

The average density value 0.79 g/cm³ at 21°C (Baldwin 2014, Bulk Density determination of Iron Gluconate) was determined in a reliable study conducted according to an appropriate standard test method (EU A3 Regulation (EC) No 440/2008, Annex, Official Journal of the European Union L142/1) using the air comparison pycnometer method per OECD 109 (27 -07 -1995).