Registration Dossier
Registration Dossier
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EC number: 264-944-7 | CAS number: 64560-69-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48h) = 24.1 mg/l
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 24.1 mg/L
Additional information
No experimental studies were available on Solvent Red 008, thus the assessment relied on a read across approach. Solvent Red 008 and Similar Substance 02 are chromium complexes with 2 ligands. In both cases, the 2 ligands have the same chemical structure, i.e. a phenyl ring connected via diazo bond to a phenyl pyrazole. These ligands show minor differences in the position of substituents, i.e. hydroxy and nitro groups, as well as in the presence of a sulfonate group in Similar Substance 02.
All information about the read across process is inserted in section 13.
In the available study on Similar Substance 01 (purity > 80 %), 20 daphnia per concentrations divided in 4 replicates were exposed to test substance under static exposure conditions. Nominal tested concentrations were 1.94, 4.25, 9.39, 20.7, 45.5 and 100 mg/l and there was evidence that the concentration of test substance was satisfactorily maintained throughout the test. The EC50 (48 h) for immobilisation was determined to be 24.1 mg/l and the corresponding NOEC (48 h) was 9.39 mg/l. The test was conducted according to OECD guideline 202.
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