Oxidation products of D-Glucose with nitric acid, sodium salts

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

16/06/2015 - 12/10/2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

A GLP study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Specific details on test material used for the study:

Sample code: 150507 GCA
Appearance: Beige Powder

Key result

Decomposition:

ambiguous

Decomp. temp.:

>= 96 - <= 146 °C

The mean of at least three measurements, which are in the range of the estimated accuracy, is reported as the melting temperature.

Conclusions:

Suspected sample decomposition was observed during four test runs between 96 oC and 145 oC. The sample was observed to expand and rise up the sample tube.

Executive summary:

The melting point of the test item was measured according to EC method A.1. Suspected sample decomposition was observed during four test runs between 96 ^oC and 145 ^oC.

Description of key information

Suspected sample decomposition was observed during four test runs between 96 ^oC and 145 ^oC.