Registration Dossier
Registration Dossier
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EC number: 203-142-3 | CAS number: 103-76-4
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
1.0E+006 mg/L
Key value for chemical safety assessment
- Water solubility:
- 1 000 000 mg/L
- at the temperature of:
- 25 °C
Additional information
Weight of evidence approach
A weight of evidence approach was conducted with the available data.
In the handbook Hommel, 2014 the test item was determined to be completely soluble. Furthermore, a QSAR Epi Suite v4.11. WATERNT calculation was conducted. The water solubility was determined to be 1000000 mg/L at 25°C.
QSAR-disclaimer
In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met. Furthermore according to Article 25 of the same Regulation testing on vertebrate animals shall be undertaken only as a last resort.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.
For the assessment of the test item (Q)SAR results were used for water solubility. The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.
Therefore, further experimental studies on water solubility are not provided.
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