Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Dermal absorption

Currently viewing:

Administrative data

Endpoint:
dermal absorption
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data taken from short database entry, not according to standard protocols

Data source

Reference
Reference Type:
secondary source
Title:
Penetrating agents.
Author:
F.Meyer
Year:
1965
Bibliographic source:
Patent, British, 1,001,949, M49750IVa/30h, 7/20/61; cited in RIFM/FEMA database, location 21664

Materials and methods

Principles of method if other than guideline:
No guideline followed

Test material

Constituent 1
Chemical structure
Reference substance name:
Geranyl acetate
EC Number:
203-341-5
EC Name:
Geranyl acetate
Cas Number:
105-87-3
Molecular formula:
C12H20O2
IUPAC Name:
3,7-dimethylocta-2,6-dien-1-yl acetate (E)-

Test animals

Species:
guinea pig

Administration / exposure

Vehicle:
other: usually 50% ethyl glycol
Duration of exposure:
2 hours
Doses:
50%
No furhter data given

Results and discussion

Any other information on results incl. tables

epithelium (epi): = (slight coloring/fluorescence)

hair follicles (hf): = (slight coloring/fluorescence)

corium (c): - (no coloring/fluorescence).

subcutis (sc): - (no coloring/fluorescence).

Applicant's summary and conclusion