Sulfuric Acid, waste gas washing, copper smelting

Acute Toxicity: oral

Administrative data

Endpoint:

acute toxicity: oral

Type of information:

calculation (if not (Q)SAR)

Remarks:

Migrated phrase: estimated by calculation

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: no GLP (but other Quality Assurance); software

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to same study

Cross-reference 2

Reason / purpose for cross-reference:

reference to other study

Data source

Reference

Reference Type:

other: software

Title:

Unnamed

Year:

2010

Materials and methods

Principles of method if other than guideline:

Acute (oral) toxicity of the UVCB substance was determined by classifying based on Mixture rules from EU CLP (summation and/or additivity of classified components to derive Hazard class) and back calculation to the corresponding Acute (oral) Toxicity criteria

GLP compliance:

no

Remarks:

equivalent Quality assurance

Test type:

other: CLP calculation software

Test material

Test material information

Constituent 1

Reference substance name:

sulfuric acid hydrate

EC Number:

922-670-1

IUPAC Name:

sulfuric acid hydrate

Details on test material:

Worst case (maximum across industry) as in iu 1.2;
See IUCLID Section 1.4, for company specific elemental composition; and representative sample for mineralogical information (IUCLID Section 4.23 -Outotec report)
Representative copper speiss - randomly collected from production over long period, crushed and homogenised

Results and discussion

Effect levels

Dose descriptor:

other:

Effect level:

> 300 - <= 2 000 other: ATE

Based on:

dissolved

Remarks on result:

other: prediction

Any other information on results incl. tables

The calculated classification via Additivity method (lower Tier Arche CLP Tool) resulted in an "Acute Oral: Category 4", driven by Arsenic acid and its salts.

Based on this result, the related criteria provided the estimated value for acute (oral) toxicity: 300 < Acute Toxicity Estimate < or equal 2000 (or subsequently to an Acute Toxicity Point Estimate of 500)

Applicant's summary and conclusion

Interpretation of results:

Toxicity Category IV

Remarks:

Migrated information Criteria used for interpretation of results: EU

Conclusions:

Result can be used to predict a ATE of the UVCB substance and to classify it (Note: constituents with unknown acute toxicity are < 1%).

Executive summary:

The study provided a conservative estimate of the Acute Oral toxicity, derived on basis of the Classification outcome (Mixture toxicity rules) from a worst case (max across industry) as defined in IUCLID section 1.4/4.23.

The result is applicable to all Sulphuric acid, waste gas cooling and cleaning, copper smelting that fall under the defined concentration ranges (IUCLID section 1.2).