Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-146-5 | CAS number: 103-80-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Guidance on Safe Use
Administrative data
First-aid measures
1. Description of first aid measures
First-aid measures general : Call a poison center or a doctor if you feel unwell.
First-aid measures after inhalation : Remove person to fresh air and keep comfortable for breathing. Call a poison center or a doctor if you feel unwell.
First-aid measures after skin contact : Wash skin with plenty of water.
First-aid measures after eye contact : Rinse eyes with water as a precaution.
First-aid measures after ingestion : Call a poison center or a doctor if you feel unwell.
2. Most important symptoms and effects, both acute and delayed
Symptoms/effects after inhalation : May cause respiratory irritation.
3. Indication of any immediate medical attention and special treatment needed
Treat symptomatically.
Fire-fighting measures
1. Extinguishing media
Suitable extinguishing media : Water spray. Dry powder. Alcohol resistant foam. Carbon dioxide.
2. Special hazards arising from the substance or mixture
Fire hazard : Carbon oxides. Hydrogen chloride.
Hazardous decomposition products in case of fire: Toxic fumes may be released.
3. Advice for firefighters
Protection during firefighting : Do not attempt to take action without suitable protective equipment. Self-contained breathing
apparatus. Complete protective clothing.
Accidental release measures
1. Personal precautions, protective equipment and emergency procedures
1.1. For non-emergency personnel
Emergency procedures : Ventilate spillage area. Avoid breathing dust/fume/gas/mist/vapours/spray.
1.2. For emergency responders
Protective equipment : Do not attempt to take action without suitable protective equipment.
2. Environmental precautions
Avoid release to the environment.
3. Methods and material for containment and cleaning up
Methods for cleaning up : Take up liquid spill into absorbent material.
Other information : Dispose of materials or solid residues at an authorized site.
Handling and storage
1. Precautions for safe handling
Precautions for safe handling : Wear personal protective equipment. Use only outdoors or in a well-ventilated area. Avoid breathing dust/fume/gas/mist/vapours/spray.
2. Conditions for safe storage, including any incompatibilities
Storage conditions : Store locked up. Store in a well-ventilated place. Keep container tightly closed. Keep cool.
Moisture sensitive.
Storage temperature : 2 - 8 °C
This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 18(4) for transported isolated intermediate. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management system is available at each site. Written confirmation of application of Strictly Controlled Conditions has been received from every Downstream user of the intermediate.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 2577
Shippingopen allclose all
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 2577
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 2577
Shipping information
- Proper shipping name and description:
- PHENYLACETYL CHLORIDE
UN 2577 PHENYLACETYL CHLORIDE, 8, II - Chemical name:
- PHENYLACETYL CHLORIDE
- Labels:
- 8
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 2577
Shipping information
- Proper shipping name and description:
- Phenylacetyl chloride
UN 2577 Phenylacetyl chloride, 8, II - Chemical name:
- PHENYLACETYL CHLORIDE
- Labels:
- 8
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Exposure controls
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Hand protection:
Protective gloves. Manipulate with gloves. Gloves have to be controlled before the use. Use a technique of withdrawal of gloves suited to avoid that the skin contacts the product (i.e. without touching the outside surface of the glove). Throw gloves contaminated after the use according to the current laws and to the good practices of laboratory. Wash and dry hands. The selected gloves have to satisfy the specifications of the EU Directive 89 / 686 / EEC and in the standard IN 374 which derives from it.
Eye protection:
Safety glasses with complete protection. Protective screen (minimum 20 cms). Tested and approved according to the current governmental standards such as NIOSH (US) or EN 166 (EU).
Skin and body protection:
Combination of protection against chemicals. The type of equipment of protection must be selected according to the concentration and to the quantity of the dangerous substance at work.
Respiratory protection:
When risk assessment shows that the breathing apparatus uilisationdes is appropriate, use a full face mask with versatile cartridge (U.S.) or type ABEK (EN 14387).
Environmental exposure controls:
Avoid release to the environment.
This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 18(4) for transported isolated intermediate. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management system is available at each site. Written confirmation of application of Strictly Controlled Conditions has been received from every Downstream user of the intermediate.
Stability and reactivity
Incompatible materials: alcohols. Water. Oxidizing agents. Strong bases.
Disposal considerations
Waste treatment methods : Dispose of contents/container in accordance with licensed collector’s sorting instructions.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
